PLEASE NOTE THAT
THERE ARE TWO LEVELS OF QUESTIONS
LEVEL ONE-30
LEVEL TWO -20
TIME – 45 minutes
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1. Acetylcholine acts through
a.
Alpha 1 and alpha 2 recptors
b.
Beta 1 and beta 2 receptors
c.
Muscarinic and nicotinic receptors
d.
Both (a) and (b)
2. An indication for use of propanalol
a.
Bradycardia
b.
Peripheral vascular disease
c.
Prinzmetal angina
d.
Essential tremor
3. Salbutomol is a
a.
Beta 1 agonist
b.
Beta 2 agonist
c.
Beta 1 antagonist
d.
Beta 2 antagonist
4. Treatment for cobra bite?
a.
Neostigmine + antisnake venom
b.
Physoostigmine + antisnakevenom
c.
Neostigmine + atropine + antisnake venom
d.
Neostigmine + adrenaline + antisnake venom
5. Drug of choice for anaphylactic shock
a.
Atropine
b.
Adrenaline
c.
Dobutamine
d.
Physostigmine
6. Which one among the following is not an adverse effect of
alpha blockers?
a.
Postural hypotension
b.
Bradycardia
c.
Impotence
d.
Nasal stuffiness
7. Which one among the following is a drug of abuse?
a.
Dobutamine
b.
Adrenaline
c.
Amphetamine
d.
Atropine
8. Organophosphates are examples of
a.
Cholinergic agonists
b.
Anticholinesterases
c.
Anticholinergic drogs
d.
Sympathomimetic drugs
9. Drug used in Pheochromocytoma
a.
Phenoxybenzamine
b.
Phentolamine
c.
Labetolol
d.
All the above
10. Beta blockers decrease intraocular tension by
a.
Increasing uveoscleral outflow
b.
Increasing trabecular outflow
c.
Decreasing aqueous humor secretion
d.
All the above
11. Which among the following amino acid is involved in
synthesis of adrenaline?
a.
Alanine
b.
Arginine
c.
Phenylalanine
d.
Threonine
12. Latanoprost is
a.
PGE2 analogue
b.
PGA2 analogue
c.
PGI2 analogue
d.
PGF2analogue
13. Enzyme involved in acetylcholine synthesis
a.
Butyrylcholinesterase
b.
Acetylcholinesterase
c.
Choline acetyl transferase
d.
Choline acylase
14. Type of muscarinic receptor in heart and its action
a.
M1,
tachycardia
b.
M2, bradycardia
c.
M3, bradycardia
d.
M4, tachycardia
15. Which one of the following is not an antagonist for
acetylcholine receptors?
a.
Atropine
b.
Adrenaline
c.
Hexamethonium
d.
Curare
16. Which among the following is a carbamate and has reversible
action?
a.
Carbaryl
b.
Edrophonium
c.
Echothiophate
d.
Tacrine
17. Rate limiting enzyme in noradrenaline synthesis
a.
Theonine hydroxylase
b.
Tyrosine hydroxylase
c.
Dopamine hydroxylase
d.
Dopa decarboxylase
18. Which among the following is the preferred miotic?
a.
Physostigmine
b.
Pilocarpine
c.
Rivastigmine
d.
Tropicamide
19. The miotic (answer for previous question) is useful in
a.
Open angle glaucoma
b.
Angle closure glaucoma
c.
Aphakic glaucoma
d.
All the above
20. Drug used to treat voiding symptoms in prostatic hyperplasia
a.
Propanalol
b.
Ergotamine
c.
Yohimbine
d.
Terazosin
21. Which one among the following is not a treatment of
belladonna poisoning?
a.
Gastric lavage with KMnO4
b.
Rest in dark room
c.
Physostigmine
d.
Diazepam
22. sympathetic receptor in bronchi that causes bronchodilatation
a.
Alpha 1
b.
Alpha 2
c.
Beta 1
d.
Beta 2
23. Which among the following is not a treatment for myasthenia
gravis?
a.
Anticholinesterase
b.
Atropine
c.
Corticosteroids
d.
Plasmapheresis
24.Which among the following is indirectly acting
sympathomimetic
a.
Phenoxybenzamine
b.
Phenylephrine
c.
Dobutamine
d.
Amphetamine
25. Cardioselective beta blocker is
a.
Propanalol
b.
Sotalol
c.
Atenolol
d.
Pindolol
26. Drug of choice for anticholinesterase poisoning
a.
Atropine
b.
Oximes
c.
Pyridostigmine
d.
Tacrine
27. Drugs used in PIPE therapy
a.
Pipaverine and ephedrine
b.
Pipaverine and esmolol
c.
Pipaverine and phentolamine
d.
Phenylephrine and phenoxybenzamine
28. Which among the following drugs is used to differentiate
between cholinergic crisis and myasthenic crisis?
a.
Physostigmine
b.
Atropine
c.
Ecothiophate
d.
Edrophonium
29. Which drug among the following is an alpha blocker?
a.
Phenylephrine
b.
Phentolamine
c.
Propanalol
d.
Phenylpropanalamine
30. Which one among the following statement is true about
atropine
a.
It selectively antagonizes M1 receptors
b.
It causes hypothermia
c.
It increases intraocular pressure in angle
closure glaucoma
d.
It causes a marked increase in gastric pH
LEVEL TWO
31. Which one among the following is a uroselective drug useful
in prostatic hyperplasia?
a.
Ergotamine
b.
Yohimbine
c.
Terazosin
d.
Tamsulosin
32. Which among the following beta blocker has alpha blocking
activity as well?
a.
Propanalol
b.
Pindolol
c.
Labetolol
d.
Atenolol
33. Which among the following is not an immediate treatment for
myasthenic crisis?
a.
Anticholinesterase
b.
Methylprednisolone
c.
Trachaeal intubation
d.
Plasmapheresis
34. Which one of the following can be used as preanasthetic
medication?
a.
Glycopyrrolate
b.
Oxybutinin
c.
Drotaverine
d.
Propantheline
35. Not a metabolic effect of propanalol
a.
Hypoglycemia
b.
Improved carbohydrate tolerance
c.
Increased LDL
d.
None of above
36. Pick the wrong statement about Rimonabant
a.
It is a cannabine receptor agonist
b.
It decreases appetite
c.
It can be used to promote smoking cessation
d.
None of the above
37. Tacrine, donepezil are primarily used
a.
As a miotic
b.
As a mydriatic
c.
In myasthenia gravis
d.
In alzheimers disease
38. Tubocurarine inhibits
a.
Nm (nicotinic muscle) receptor
b.
Nn (nicotinic ganglion) receptor
c.
Muscarinic receptor
d.
All the above
39. Dopamine is mainly used in
a.
Hypertension
b.
Asthma
c.
Mydriatic
d.
Shock
40. Drug used in amphetamine toxicity
a.
Caffeine
b.
Chlorpromazine
c.
Chlorphenyramine
d.
Chloroquine
41. Hemorrhagic stroke is a risk associated with
a.
Phenylpropanolamine
b.
Pseudoephedrine
c.
Mepheneteramine
d.
Xylometazoline
42. Beta blocker that causes vasodilatation by NO production
a.
Pindolol
b.
Nebivolol
c.
Sotalol
d.
Carvedilol
43. Which among the following form of cholinesterase reacts very
slowly with water?
a.
Acetylated form
b.
Acylated form
c.
Carbamylated form
d.
Phosphorylated form
44. Alpha 2 agonist is
a.
Yohimbine
b.
Clonidine
c.
Prazosin
d.
Phenylephrine
45. Drug of choice for topical use in eyes in acute angle
closure glaucoma
a.
Pilocarpine
b.
Latonoprost
c.
Timolol
d.
Betaxolol
46. False statement
a.
Atropine is used in the treatment of mushroom
poisoning by Amanita muscaria
b.
Amanita phalloides causes late mushroom
poisoning
c.
Cholinergic drugs delay AV nodal conduction
d.
Cholinergic drugs cause vasodilatation through
Nitric oxide
47. Which among the following is not a use of adrenaline?
a.
To control local bleeding
b.
Along with general anaesthetics like chloroform
and halothane
c.
In cardiac arrest
d.
None of the above
48. Ipratropium is more effective in
a.
COPD
b.
Bronchial asthma
c.
Gastro-intestinal colic
d.
Urge incontinence
49. Pick the right statements
a.
Oximes are useful in all anticholinesterase poisoning
b.
Oximes are ineffective if not used within 24 hrs
c.
Oximes are the first choice drugs for
anticholinesterase poisoning
d.
Pralidoxime is effective in reversing the CNS
effects of anticholinesterases
50. Drug used to delay preterm labour
a.
Ritodrine
b.
Dipivefrine
c.
Drotaverine
d.
valethemide
